From Suppression to Resetting: Outlining a New Era in an Evolving Therapeutic Landscape for Autoimmunity
- Identifying the clinical and molecular criteria that differentiate a true ‘immune reset’ from traditional immune suppression techniques
- Understanding the current landscape of modalities achieving deep depletion of pathogenic immune memory cells necessary for immune rebooting
- Diving into the current hurdles to making immune resetting therapies a standard of care such as manufacturing scalability, off-target effects, safety and developing biomarkers