Exploring Autologous CD-19 CAR-Ts for Rheumatology to Advance Treatment Development for Orphan Diseases

  • Discussing the emerging clinical data showing deep, sustained B-cell depletion in Lupus patients
  • Exploring whether depth of depletion translates into long-term, drug-free remission that has been unattainable with conventional treatments
  • Identifying signatures in the repopulating B-cell and T-cell compartments that predict durable remission and guide the regulatory pathway for a curative therapy