Immune Resetting: B-Cell Mediated & Beyond Summit – FAQs

The Immune Resetting: B-Cell Mediated & Beyond Summit is the world’s first and only meeting dedicated to advancing immune resetting strategies for autoimmune disease.

Taking place in Boston, this focused event unites global leaders driving innovation across:

• Deep B-cell depletion and drug-free remission
• CAR-T and in vivo cell engineering for autoimmunity
• T-cell engagers (TCEs) and bispecific antibodies
• Engineered Tregs and antigen-specific tolerance platforms
• Translational biomarkers, trial design, and regulatory endpoints

As the most specialized immune resetting conference, it provides a unique platform to explore mechanisms, modalities, and clinical strategies shaping the next generation of autoimmune therapies.

The summit is designed for professionals advancing immune resetting approaches from discovery through clinical and commercial development.
Attendees typically include:

• Autoimmune Cell Therapy & Immunology R&D Leaders
• CAR-T, TCE, and bispecific antibody developers
• Treg therapy and tolerance platform innovators
• Translational medicine and clinical development teams
• Biomarker and immune monitoring specialists
• Academic researchers in autoimmunity and immune tolerance

This is the must-attend meeting for anyone working across immune resetting, autoimmune TCEs and cell therapies, and next-generation biologics.

The 2026 agenda addresses the most urgent scientific, technical, and commercial challenges in immune resetting, including:

• Defining immune reset: biomarkers, naïve B-cell reconstitution, autoantibody clearance
• CAR-T for autoimmunity: CD19, CD20, CD38, and BCMA targeting
• T-cell engagers (TCEs): CD3 affinity tuning, CRS mitigation, tissue targeting
• Engineered Tregs: stability, persistence, and endpoints for tolerance restoration
• Clinical trial design: endpoints, dose-finding, and regulatory pathways
• Safety management: CRS, infections, hypogammaglobulinemia

By attending, participants will:

• Gain first-hand insight into emerging clinical data and immune reset biomarkers
• Benchmark strategies for CAR-T, TCEs, Tregs, and antibody therapeutics
• Network with the world’s most concentrated immune resetting community
• Stay ahead in a rapidly evolving autoimmune therapy landscape

Unlike broader autoimmunity or immunology meetings, IRBC is exclusively focused on exclusively focused on immune resetting across multiple modalities.

This specialization enables deeper technical discussions, more relevant networking, and unmatched insight into mechanistic and translational challenges compared with general autoimmune or immuno-oncology events.

The summit will covers all major approaches:

• CAR-T therapies (CD19, CD20, CD38, BCMA) for deep B-cell depletion
• In vivo cell engineering for scalable autoimmune intervention
• T-cell engagers (TCEs) for precision depletion with outpatient potential
• Engineered Tregs for restoring tolerance and preventing relapse
• Antigen-specific tolerance platforms for targeted immune education

You can register directly through the “Register” section on the website (ensure you review the pricing & registration details). Alternatively, contact us at info@hansonwade.com and a member of our team will be in touch shortly.

Group discounts of up to 20% are available when you attend with 4 or more colleagues. Attend with a colleague for a 10% discount.

View full registration details here.

For enquiries regarding registration, speaking opportunities or press, please contact info@hansonwade.com. For sponsorship enquiries, please contact sponsor@hansonwade.com.

Or view our Contact Us page.